Personalized cellular products: balancing accessibility and demand for breakthrough therapies
https://doi.org/10.60043/2949-5938-2025-1-6-9
Abstract
Genome editing systems are powerful tools capable of precisely modifying genetic material in its natural context within a living organism. Thanks to these remarkable capabilities, editing systems have found a wide range of applications in all areas of biological science and medicine. In this manuscript, we provide a brief historical overview of the origins and development of various genome editing systems. The evolution of this field has been accompanied by significant discoveries and the awarding of numerous Nobel Prizes. Tracing the logic of scientific thought in the quest to understand and modify the material basis of heredity, this manuscript aims to provide budding researchers with a comprehensive picture of the vast (literally) universe of genome editing systems. Understanding the full spectrum of potential activity of editing systems obliges researchers to use them thoughtfully and responsibly.to the article yet reasonably common within the subject discipline.
About the Author
P. I. MakarevichRussian Federation
Pavel I. Makarevich — Dr. Sci. (Medicine), Head of the Laboratory of Medical Bioengineering at the Center for Regenerative Medicine of the Medical Scientific and Educational Institute at Lomonosov Moscow State University; Associate Professor of the Department of Biochemistry and Regenerative Biomedicine at the Faculty of Medicine at Lomonosov Moscow State University.
119192, Moscow Lomonosovskiy ave., 27, bld. 10; 121552, Moscow, Academician Chazov str., 15A
Competing Interests:
The author has been a member of the editorial board of the journal “Organ and Tissue Regeneration” since 2023 but had no role in the decision to publish this article.
This article has undergone the journal’s established peer-review process; the author’s opinion is his or her own and does not reflect the position of any supervisory or expert bodies.
Review
For citations:
Makarevich P.I. Personalized cellular products: balancing accessibility and demand for breakthrough therapies. Регенерация органов и тканей. 2025;3(1):6-9. (In Russ.) https://doi.org/10.60043/2949-5938-2025-1-6-9
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